autism_de_novos: get de novo data from autism exome studies

In jeremymcrae/publishedDeNovos: Published De Novos Dataset from Developmental Disorder Sequencing Studies

Description

I think this data was obtained from studies published using the Simon's Simplex Collection data (http://sfari.org/resources/simons-simplex-collection)

Usage

autism_de_novos()

Details

Supplementary table 2 (where the excel sheets for the probands and siblings have been combined) from: Sanders et al. (2012) Nature 485:237-241 doi: 10.1038/nature10945

Supplementary table 3 from: O'Roak et al. (2012) Nature 485:246-250 doi: 10.1038/nature10989

Supplementary table 1 (where the non-coding SNVs have been excluded) and supplementary table 2 from: Iossifov et al. (2012) Neuron 74:285-299 doi: 10.1016/j.neuron.2012.04.009

Value

data frame of de novos, including gene symbol, functional consequence (VEP format), chromosome, nucleotide position and SNV or INDEL type

jeremymcrae/publishedDeNovos documentation built on May 19, 2019, 5:08 a.m.