heatmap_diff_methylation_in_genomic_features: Heatmap for differential methylated genomic features

Description Usage Arguments Details Value Author(s) Examples

View source: R/methylation_genomic_features.R

Description

Heatmap for differential methylated genomic features

Usage

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heatmap_diff_methylation_in_genomic_features(gr, subgroup,
    ha = HeatmapAnnotation(subgroup = subgroup, show_annotation_name = TRUE),
    genomic_features = NULL,
    meth_diff = 0, cutoff = 0.05, adj_method = "BH",
    cluster_columns = c("subgroup", "all", "none"), ...)

Arguments

gr

a GRanges object returned from get_mean_methylation_in_genomic_features

subgroup

subgroup information

ha

column annotations, a HeatmapAnnotation-class object

genomic_features

a single or a list of GRanges objects that are used to annotate gr

meth_diff

minimal range between mean value in subgroups

cutoff

if subgroup information is provided, cutoff of p-value of the oneway ANOVA test

adj_method

method to calculate adjusted p-values

cluster_columns

how to cluster columns. "subgroup" means only to cluster samples in every subgroup.

...

pass to Heatmap

Details

Only those regions having differential methylation are visualized.

Value

A GRanges object which only contains regions with significant differential methylation.

Author(s)

Zuguang Gu <z.gu@dkfz.de>

Examples

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# There is no example
NULL

jokergoo/epik documentation built on Sept. 28, 2019, 9:20 a.m.