README.md

mutSigMapper

R package mutSigMapper aims to resolve a critical shortcoming of existing software for mutational signature analysis, namely that of finding parsimonious and biologically plausible exposures. By implementing a shot-noise-based model to generate spectral ensembles, this package addresses this gap and provides a quantitative, non-parametric assessment of statistical significance for the association between mutational signatures and observed spectra.

To install: install.packages("devtools") # if you have not installed the "devtools" package devtools::install_github("juliancandia/mutSigMapper")



juliancandia/mutSigMapper documentation built on Oct. 19, 2020, 3:58 a.m.