Description Usage Arguments Details Value Author(s) See Also
Finds mean of the distribution of statistics generated from overexpressed nucleotides
1 | find.mean.up(init.value, null.mean, null.sd, null.prop, vals)
|
init.value |
number in (0.5, 1) representing a percentile of the null distribution to use as starting value |
null.mean |
estimated mean of null distribution (usually found with locfdrFit) |
null.sd |
estimated standard deviation of null distribution (usually found with locfdrFit) |
null.prop |
estimated proportion of statistics that came from the null distribution |
vals |
vector of all the observed values from the mixture distribution |
This function is for experienced users or debugging only -
all other users should use getParams
, which calls
this function.
If numerical method succeeds, a list with elements
If numerical method fails, a list with elements
m
|
estimated mean of the underexpressed distribution, and |
p |
the percentile of the null distribution used to find this mean |
If numerical method fails, a list with elements
m |
mean of underexpressed distribution, as estimated by the 5th percentile of the estimated null distribution |
s |
standard deviation of underexpressed distribution, as estimated by the standard deviation of the null distribution |
Alyssa Frazee
getParams
, find.mean.down
,
find.sd
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