find.sd: Helper function for getParams

In leekgroup/derfinder: Differential expression analysis of RNA-seq data at base-pair resolution

Description

Find standard deviation of distribution of over- or underexpressed statistics

Usage

find.sd(prev.p, found.mean, null.mean, null.sd, null.prop, vals, up = T)

Arguments

prev.p	percentile of null distribution used to find the mean of the distribution of interest - usually the $p return of find.mean.up or find.mean.down.
found.mean	mean of distribution of interest - usually the $m return of find.mean.up or find.mean.down
null.mean	estimated mean of null distribution (usually found with locfdrFit)
null.sd	estimated standard deviation of null distribution (usually found with locfdrFit)
null.prop	estimated proportion of statistics that came from the null distribution
vals	vector of all the observed values from the mixture distribution
up	if TRUE, find standard deviation of overexpressed statistics, otherwise find standard deviation of underexpressed statistics

Details

This function is for experienced users or debugging only - all other users should use getParams, which calls this function.

Value

The estimated standard deviation of the over- or underexpressed statistics

Author(s)

Alyssa Frazee

See Also

getParams, find.mean.up, find.mean.down

leekgroup/derfinder documentation built on May 20, 2019, 11:30 p.m.