fitIAI_mod: Re-implemented IAI calculation with model selection and CI

In lshen1/drexplorer2: Dose-response Explorer2

Description

Re-implemented IAI calculation with model selection and CI

Usage

fitIAI_mod(
  d1,
  d2,
  e,
  E = seq(0.05, 0.95, 0.005),
  name1 = "Drug A",
  name2 = "Drug B",
  ratio,
  tol = 0.1,
  IAIactive = 0.95
)

Arguments

d1	dose for drug 1.
d2	dose for drug 2.
e	corresponding percentile in the range [0, 1]; response is 1-E.
E	a vector of responses (between 0 and 1) where IAI and confidence interval are to be computed from.
name1	drug 1 name.
name2	drug 2 name.
ratio	ratio of d1/d2.
tol	tolerance in declaring fixed ratio.
IAIactive	default is set to 0.95.

Value

a list

Examples

fitL_mod <- fitIAI_mod(d1 = UMSCC22B[, 1], d2 = UMSCC22B[, 2], e = UMSCC22B[, 3],
                       name1 = 'SCH66336', name2 = '4HPR', ratio = 1)

lshen1/drexplorer2 documentation built on June 2, 2020, 9:27 p.m.