TF_GSEA | R Documentation |
A unified Gene Set Enrichment Analysis (GSEA) function for three methods
TF_GSEA(GSDB, DErslt, minSize = 5, nperm = 1000, method = "binary")
GSDB |
gene set database (a list of gene sets, each of which is comprised of a vector genes) |
DErslt |
DEG results |
minSize |
the minimum number of overlapping genes required for each gene set (a gene set filtering parameter, default: 5) |
nperm |
the number of gene list permutations (default: 1000) |
method |
fast: fgsea; r: R implementation of GSEA with a new permutation method; binary: R/C++ implementation for fast speed |
gseaRes: a table of GSEA results: tf: TF (gene set name). es: ES score. lens: number of overlapping genes in each gene set. pvals: p-value by counting. z: z-score. qvals: q-value from pvals.
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