applyDPI: Apply data processing inequality

In lusystemsbio/NetAct: NetAct -- a computational platform to construct core transcription factor regulatory networks using gene activity

Apply data processing inequality

Description

Remove the interactions from a triangle which have lowest interaction score.

Usage

applyDPI(tfLinks = tfLinks, miMat = miMat, miDiff = 0, minMiTh = 0.5)

Arguments

tfLinks	Data.frame. containing the interactions as source (character), target (character), type (integer).
miMat	numeric matrix. Interaction scores based on mutual information or correlation.
miDiff	numeric (0-1). Default 0.0 (optional) Minimum difference between mutual information of a traingle for the edge to be removed.
minMiTh	numeric (0-1). Default 0.5. Minimum value of MI for an interaction which will not be removed.

Value

data.frame. containing the filtered interactions.

lusystemsbio/NetAct documentation built on Sept. 7, 2024, 8:34 p.m.