knitr::opts_chunk$set(echo = TRUE)
sracipeHeatmapSimilarity()

A crucial aspect for network modeling is to evaluate whether the simulations capture the essential features of the experimental data or not. This comparison will help in finetuning the network or parameters.

In sRACIPE, the function sracipeHeatmapSimilarity can compare two expression datasets and return a similarity score. One can provide the experimental data and simulated data as two datasets. If the clusters for the experimental data are not provided, then the data is clustered using hierarchical clustering. Then each model in the simulated data is compared with each cluster using correlation of expression values.



lusystemsbio/sRACIPE documentation built on Nov. 19, 2024, 9:07 a.m.