sigidentEnrichment: Perform Enrichtment Analysis in Gene Expression Datasets...

View source: R/sigidentEnrichment.R

sigidentEnrichmentR Documentation

Perform Enrichtment Analysis in Gene Expression Datasets Derived from MicroArrays

Description

One function to perform gene enrichment analysis.

Usage

sigidentEnrichment(
  mergedset,
  mergeset,
  idtype,
  diagnosis,
  species,
  org_db,
  organism,
  pathwayid,
  plotdir = "./plots/",
  csvdir = "./tables/"
)

Arguments

mergedset

A large merged Expression Data set. The output of the funtion 'sigident.preproc::load_geo_data()'.

mergeset

A matrix of merged expression sets (rows = genes, columns = samples). The output of the funtion 'sigident.preproc::load_geo_data()'.

idtype

A character string. The type of ID used to name the genes. One of 'entrez' or 'affy' intended to use either entrez IDs or affy IDs. Caution: when using entrez IDs, missing and duplicated IDs are being removed!

diagnosis

A vector of integers, holding the binary outcome variable (0 = "Control", 1 = "Target").

species

A character string indicating the sample's species. Currently supported: "Hs".

org_db

A character string indicating the OrgDb. Currently supported: "org.Hs.eg.db".

organism

A character string indicating the organism. Currently supported: "hsa".

pathwayid

A character string indicating the pathway to show in the enrichment analysis. Currently supported: "hsa04110".'

plotdir

A character string. Path to the folder to store resulting plots. Default: "./plots/".

csvdir

A character string. Path to the folder to store output tables. Default: "./tables/".


miracum/clearly-sigident.func documentation built on June 28, 2022, 3:16 p.m.