run_tSig: Wrapper Function

In mskcc/tempoSig: Maximum Likelihood Fitting of Mutational Catalogs and De Novo Inference of Signatures

Wrapper Function

Description

One-step execution of exposure inference, filtering, and output

Usage

run_tSig(
  catalog,
  signat = "v2",
  nperm = 1000,
  alpha = 0.05,
  output = "exposure.txt"
)

Arguments

catalog	Catalog input file
signat	Reference signature choices, c('v2','SA','SP') for sCOSMIC v2, SigAnalyzer, and sigProfiler, respectively
nperm	No. of permutations
alpha	False positive rate threshold
output	Output file

mskcc/tempoSig documentation built on Feb. 3, 2023, 8:35 a.m.