CELLector.RecfiltVariants: Somatic mutations recurrently observed in cancer

In najha/CELLector: Genomics guided selection of cancer cell lines

Somatic mutations recurrently observed in cancer

Description

Somatic variant passing a recurrence based threshold (defined in [1]) in COSMIC [2]

Usage

data("CELLector.RecfiltVariants")

Format

A vector of string with one entry per variant. Each string is a space delimited list of three elements: The HUGO symbol of the gene hosting the variant, a string codifying the effect of the variant on cDNA, a string codifying the effect of the variant in terms of aminoacid substitutions.

References

[1] Iorio, F. et al. A Landscape of Pharmacogenomic Interactions in Cancer. Cell 166, 740–754 (2016).

[2] Forbes, S. A. et al. COSMIC: exploring the world’s knowledge of somatic mutations in human cancer. Nucleic Acids Res. 43, D805–11 (2015).

Examples

data(CELLector.RecfiltVariants)
head(CELLector.RecfiltVariants)

najha/CELLector documentation built on Feb. 8, 2023, 5:35 a.m.