Description Usage Arguments Value
simulate betas for a study
simulate_study
use the multivariate normal to simulate realistic betas for a study
1 | simulate_study(DT, ref_gt_dir, shrink_beta = TRUE, n_sims = 10, quiet = TRUE)
|
DT |
a data.table - as returned by |
ref_gt_dir |
scalar - path to a dir of R objects named CHR_1kg.RData containing reference GT in snpMatrix format |
shrink_beta |
scalar - Whether to use Bayesian shrinkage of betas (default = TRUE) |
n_sims |
a scalar - number of simulations (default 10) |
quiet |
a scalar - boolean whether to show progress messages |
a DT of n_sims simulated studies for projection
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