simulate_study: simulate betas for a study 'simulate_study' use the...

Description Usage Arguments Value

View source: R/simulate.R

Description

simulate betas for a study simulate_study use the multivariate normal to simulate realistic betas for a study

Usage

1
simulate_study(DT, ref_gt_dir, shrink_beta = TRUE, n_sims = 10, quiet = TRUE)

Arguments

DT

a data.table - as returned by get_gwas_data

ref_gt_dir

scalar - path to a dir of R objects named CHR_1kg.RData containing reference GT in snpMatrix format

shrink_beta

scalar - Whether to use Bayesian shrinkage of betas (default = TRUE)

n_sims

a scalar - number of simulations (default 10)

quiet

a scalar - boolean whether to show progress messages

Value

a DT of n_sims simulated studies for projection


ollyburren/cupcake documentation built on July 30, 2020, 9:58 a.m.