sorensenIndex: Sorensen index

In shashidhar22/LymphoSeq2: Analyze high-throughput sequencing of T and B cell receptors

Sorensen index

Description

Calculates the Sorensen index between two groups of repertoires. Similar to a Jaccard index, Sorensen index gives a greater weight to shared sequences over unique sequences.

Usage

sorensenIndex(sample_list)

Arguments

sample_list

A list of two tibble corresponding derived from the productiveSeq() function in LymphoSeq2. "duplicate_frequency", "junction_aa", and "repertoire_id" columns are necessary for the calculation of the Bhattacharyya coefficient.

Value

Returns the similarity score, a measure of the amount of overlap between two samples. The value ranges from 0 to 1 where 1 indicates the sequence frequencies are identical in the two samples and 0 indicates no shared frequencies.

See Also

scoringMatrix()

shashidhar22/LymphoSeq2 documentation built on Jan. 16, 2024, 4:29 a.m.