dot-boottest: Bootstrap Procedure for Testing Statistical Significance of...

.boottestR Documentation

Bootstrap Procedure for Testing Statistical Significance of Correlation Values

Description

Statistical significance of correlations between pairs of taxonomic units is tested using a bootstrap procedure as proposed by Friedman and Alm (2012).

Usage

.boottest(
  countMat,
  assoMat,
  nboot = 1000,
  measure,
  measurePar,
  cores = 4,
  logFile = NULL,
  verbose = TRUE,
  seed = NULL,
  assoBoot = NULL
)

Arguments

countMat

matrix containing microbiome data (read counts) for which the correlations are calculated (rows represent samples, columns represent taxa)

assoMat

matrix containing associations that have been estimated for countMat.

nboot

number of bootstrap samples.

measure

character specifying the method used for computing the associations between taxa.

measurePar

list with parameters passed to the function for computing associations/dissimilarities. See details for the respective functions.

cores

number of CPU cores used for parallelization.

logFile

character defining a log file, where the number of iteration is stored. If NULL, no log file is created. wherein the current iteration numbers are stored.

verbose

logical; if TRUE, the iteration numbers are printed to the R console

seed

an optional seed for reproducibility of the results.

assoBoot

list with bootstrap association matrices.

Value

pvals calculated p-values
corrMat estimated correlation matrix

References

\insertRef

friedman2012inferringNetCoMi


stefpeschel/NetCoMi documentation built on Feb. 4, 2024, 8:20 a.m.