bbTest: Differential expression using beta-binomial models

In tangchao7498/ICAS:

Description

Identifies differentially expressed SJs between two groups of cells using a beta-binomial models

Usage

bbTest(object, cells.1, cells.2, genes.use, print.bar = TRUE,
  maxit = 10, confounder = NULL, NT = 1)

Arguments

object	ICASDataSet object
cells.1	Group 1 cells
cells.2	Group 2 cells
genes.use	SJs to use for test
print.bar	Print a progress bar
maxit	maximum number of (usually Fisher-scoring) iterations allowed. Decreasing maxit speeds up the function, but can weaken statistical reliability.
confounder	The confounder to regress out.
NT

Value

Returns a p-value ranked matrix of putative differentially expressed SJs.

tangchao7498/ICAS documentation built on Jan. 28, 2021, 3:56 p.m.