drivingforce.inferTRN: Inferring significant TF->TF and TF->TG interactions based on...

In xu-lab/SINCERA: An R implementation of SINCERA pipeline for processing single-cell RNA-seq data.

Description

Inferring significant TF->TF and TF->TG interactions based on gene expression patterns

Usage

drivingforce.inferTRN(object, groups = NULL, use.scaled = T,
  use.allcells = T, ...)

Arguments

object	A sincera object
groups	The cell groups for network inference
use.scaled	If TRUE, use the zscore scaled expression values for the inference
use.allcells	If TRUE, the expression values of all cells will be used for inference; otherwise, only the expression values in the cell group will be used for inference.

Value

An update sincera object, use getDF with name="edges" to access the significance of all interactions

xu-lab/SINCERA documentation built on Feb. 3, 2021, 4:19 a.m.