exprs.synthetic.similarity: Calculating the similarity between each gene profile and...

In xu-lab/SINCERA: An R implementation of SINCERA pipeline for processing single-cell RNA-seq data.

Description

Calculating the similarity between each gene profile and group specific synthetic reference expression profile synthetic profile is created by setting fpkm(cluster cells)=1, fpkm(non cluster cells)=0

Usage

exprs.synthetic.similarity(ES, group.by = CLUSTER.LABEL, groups = NULL,
  syn.sim.prefix = SYN.SIM.PREFIX)

Arguments

ES	(ExpressionSet) an ExpressionSet object containing the single cell RNA-seq data
group.by	(character) the name of the column that contains the cluster information
groups	(character) the clusters for signature prediction
syn.sim.prefix	(character) prefix for labeling the columns encoding the results of synthetic profile similarity metric for each group

Value

an ExpressionSet object containing the results of synthetic profile similarity metrics in the attributes of fData

xu-lab/SINCERA documentation built on Feb. 3, 2021, 4:19 a.m.