Description Usage Arguments Value
This function is a wrapper that executes all steps of SC3 analysis in one go.
1 2 3 4 5 6 7 8 9 10 11 12  | sc3.SingleCellExperiment(object, ks, gene_filter, pct_dropout_min,
  pct_dropout_max, d_region_min, d_region_max, svm_num_cells, svm_train_inds,
  svm_max, n_cores, kmeans_nstart, kmeans_iter_max, k_estimator, biology,
  rand_seed)
## S4 method for signature 'SingleCellExperiment'
sc3(object, ks = NULL, gene_filter = TRUE,
  pct_dropout_min = 10, pct_dropout_max = 90, d_region_min = 0.04,
  d_region_max = 0.07, svm_num_cells = NULL, svm_train_inds = NULL,
  svm_max = 5000, n_cores = NULL, kmeans_nstart = NULL,
  kmeans_iter_max = 1e+09, k_estimator = FALSE, biology = FALSE,
  rand_seed = 1)
 | 
object | 
 an object of   | 
ks | 
 a range of the number of clusters   | 
gene_filter | 
 a boolen variable which defines whether to perform gene filtering before SC3 clustering.  | 
pct_dropout_min | 
 if   | 
pct_dropout_max | 
 if   | 
d_region_min | 
 defines the minimum number of eigenvectors used for 
kmeans clustering as a fraction of the total number of cells. Default is   | 
d_region_max | 
 defines the maximum number of eigenvectors used for 
kmeans clustering as a fraction of the total number of cells. Default is   | 
svm_num_cells | 
 number of randomly selected training cells to be used 
for SVM prediction. The default is   | 
svm_train_inds | 
 a numeric vector defining indeces of training cells 
that should be used for SVM training. The default is   | 
svm_max | 
 define the maximum number of cells below which SVM is not run.  | 
n_cores | 
 defines the number of cores to be used on the user's machine. If not set, 'SC3' will use all but one cores of your machine.  | 
kmeans_nstart | 
 nstart parameter passed to   | 
kmeans_iter_max | 
 iter.max parameter passed to   | 
k_estimator | 
 boolean parameter, defines whether to estimate an optimal number of clusters   | 
biology | 
 boolean parameter, defines whether to compute differentially expressed genes, marker genes and cell outliers.  | 
rand_seed | 
 sets the seed of the random number generator.   | 
an object of SingleCellExperiment class
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.