ScanStatRefineComp: Main refining window scan statistics computation

In SeqCNVCBS: Scan Statistics for CNV Detection with CBS

Description

This is a wrapper function to call the C routines for the scan statistic to refine current candidate segmentations computing from the IGS

Usage

ScanStatRefineComp(combZCumSum, combXCumSum, combZPoint, combXPoint, p, nTotal, grid.cur, grid.LR, max.win, statistic)

Arguments

combZCumSum	A cumulative sum of the number of case reads
combXCumSum	A cumulative sum of the number of reads
combZPoint	The number of case reads at the grid points
combXPoint	The number of reads at the grid points
p	The proportion of case reads in the current region
nTotal	The total number of reads in the current region
grid.cur	The current grid to be computed on
grid.LR	The left and right limits of the existing candidate segmentations that will be refined, indexed by the current grid
max.win	The maximum inter-window to be considered for new scan
statistic	The type of statistic. Can be 'binomial','rabinowitz', 'normal', or 'hybrid'

Details

The computations are done in C for speed.

Value

Returns a matrix containing the refined candidate change points

Author(s)

Jeremy J. Shen

See Also

ScanCBS, ScanIterateGrid

SeqCNVCBS documentation built on May 2, 2019, 6:51 p.m.