CancerMutationAnalysis: Cancer mutation analysis
Version 1.18.0

This package implements gene and gene-set level analysis methods for somatic mutation studies of cancer. The gene-level methods distinguish between driver genes (which play an active role in tumorigenesis) and passenger genes (which are mutated in tumor samples, but have no role in tumorigenesis) and incorporate a two-stage study design. The gene-set methods implement a patient-oriented approach, which calculates gene-set scores for each sample, then combines them across samples; a gene-oriented approach which uses the Wilcoxon test is also provided for comparison.

Package details

AuthorGiovanni Parmigiani, Simina M. Boca
Bioconductor views Genetics Software
MaintainerSimina M. Boca <[email protected]>
LicenseGPL (>= 2) + file LICENSE
Version1.18.0
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
source("https://bioconductor.org/biocLite.R")
biocLite("CancerMutationAnalysis")

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CancerMutationAnalysis documentation built on May 31, 2017, 11:55 a.m.