CancerMutationAnalysis: Cancer mutation analysis

This package implements gene and gene-set level analysis methods for somatic mutation studies of cancer. The gene-level methods distinguish between driver genes (which play an active role in tumorigenesis) and passenger genes (which are mutated in tumor samples, but have no role in tumorigenesis) and incorporate a two-stage study design. The gene-set methods implement a patient-oriented approach, which calculates gene-set scores for each sample, then combines them across samples; a gene-oriented approach which uses the Wilcoxon test is also provided for comparison.

Package details

AuthorGiovanni Parmigiani, Simina M. Boca
Bioconductor views Genetics Software
MaintainerSimina M. Boca <>
LicenseGPL (>= 2) + file LICENSE
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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CancerMutationAnalysis documentation built on Nov. 8, 2020, 6:47 p.m.