Methods to cluster and analyze high-throughput single cell immune cell repertoires, especially from the 10X Genomics VDJ solution. Contains an R interface to CD-HIT (Li and Godzik 2006). Methods to visualize and analyze paired heavy-light chain data. Tests for specific expansion, as well as omnibus oligoclonality under hypergeometric models.
|Author||Andrew McDavid [aut, cre], Yu Gu [aut], Erik VonKaenel [aut], Thomas Lin Pedersen [ctb]|
|Bioconductor views||Clustering ImmunoOncology RNASeq SingleCell TargetedResequencing Technology Transcriptomics|
|Maintainer||Andrew McDavid <Andrew_McDavid@urmc.rochester.edu>|
|Package repository||View on Bioconductor|
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