enrichDGNv: enrichDGN

Description Usage Arguments Details Value Author(s) References

View source: R/enrichDGNv.R

Description

Enrichment analysis based on the DisGeNET (http://www.disgenet.org/)

Usage

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enrichDGNv(
  snp,
  pvalueCutoff = 0.05,
  pAdjustMethod = "BH",
  universe,
  minGSSize = 10,
  maxGSSize = 500,
  qvalueCutoff = 0.2,
  readable = FALSE
)

Arguments

snp

a vector of SNP

pvalueCutoff

pvalue cutoff

pAdjustMethod

one of "holm", "hochberg", "hommel", "bonferroni", "BH", "BY", "fdr", "none"

universe

background genes

minGSSize

minimal size of genes annotated by NCG category for testing

maxGSSize

maximal size of each geneSet for analyzing

qvalueCutoff

qvalue cutoff

readable

whether mapping gene ID to gene Name

Details

given a vector of genes, this function will return the enrichment NCG categories with FDR control

Value

A enrichResult instance

Author(s)

Guangchuang Yu

References

Janet et al. (2015) DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes. Database bav028 http://database.oxfordjournals.org/content/2015/bav028.long


DOSE documentation built on Nov. 8, 2020, 7:48 p.m.