Dynamic Transcriptome Analysis

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Description

The DTA package implements all methods of the quantitative kinetic modeling approach belonging to DTA (Dynamic Transcriptome Analysis) to estimate mRNA synthesis and decay rates from individual time point measurements.

Details

Package: DTA
Type: Package
Version: 2.0.1
Date: 2012-03-22
License: Artistic-2.0
LazyLoad: yes

Author(s)

Bjoern Schwalb <schwalb@lmb.uni-muenchen.de>

References

C. Miller, B. Schwalb, K. Maier, D. Schulz, S. Duemcke, B. Zacher, A. Mayer, J. Sydow, L. Marcinowski, L. Doelken, D. E. Martin, A. Tresch, and P. Cramer. Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast. Mol Syst Biol, 7:458, 2011. M. Sun, B. Schwalb, D. Schulz, N. Pirkl, L. Lariviere, K. Maier, A. Tresch, P. Cramer. Mutual feedback between mRNA synthesis and degradation buffers transcript levels in a eukaryote. Under review. B. Schwalb, B. Zacher, S. Duemcke, D. Martin, P. Cramer, A. Tresch. Measurement of genome-wide RNA synthesis and decay rates with Dynamic Transcriptome Analysis (DTA/cDTA). Bioinformatics.

Examples

1
## see vignette or supplemental material of the given references.

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