cDTA normalization procedure.

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Description

DTA.normalize can normalize expression values from a certain species to the median of values from a reference species.

Usage

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DTA.normalize(mat,reliable = NULL,logscale = FALSE,protocol = FALSE,center = FALSE)

Arguments

mat

Expression matrix.

reliable

The rows to be used, i.e. identifiers of the reference species to normalize on.

logscale

Is the matrix in log-scale ?

protocol

Should a protocol be printed ?

center

Should the center be 0 (log-scale) or 1 (absolute scale). Otherwise the median of the medians is taken.

Author(s)

Bjoern Schwalb schwalb@lmb.uni-muenchen.de

References

M. Sun, B. Schwalb, D. Schulz, N. Pirkl, L. Lariviere, K. Maier, A. Tresch, P. Cramer. Mutual feedback between mRNA synthesis and degradation buffers transcript levels in a eukaryote. Under review. B. Schwalb, B. Zacher, S. Duemcke, D. Martin, P. Cramer, A. Tresch. Measurement of genome-wide RNA synthesis and decay rates with Dynamic Transcriptome Analysis (DTA/cDTA). Bioinformatics.

Examples

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### see vignette examples or reference:
### B. Schwalb, B. Zacher, S. Duemcke, D. Martin, P. Cramer, A. Tresch.
### Measurement of genome-wide RNA synthesis and decay rates with Dynamic Transcriptome Analysis (DTA/cDTA). Bioinformatics, in revision.

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