DepecheR: Determination of essential phenotypic elements of clusters in high-dimensional entities

The purpose of this package is to identify traits in a dataset that can separate groups. This is done on two levels. First, clustering is performed, using an implementation of sparse K-means. Secondly, the generated clusters are used to predict outcomes of groups of individuals based on their distribution of observations in the different clusters. As certain clusters with separating information will be identified, and these clusters are defined by a sparse number of variables, this method can reduce the complexity of data, to only emphasize the data that actually matters.

Package details

AuthorJakob Theorell [aut, cre], Axel Theorell [aut]
Bioconductor views CellBasedAssays Classification Clustering DataRepresentation DifferentialExpression DimensionReduction FeatureExtraction FlowCytometry ImmunoOncology RNASeq SingleCell Software Transcription Transcriptomics Visualization
MaintainerJakob Theorell <jakob.theorell@ndcn.ox.ac.uk>
LicenseMIT + file LICENSE
Version1.6.0
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DepecheR")

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DepecheR documentation built on Nov. 8, 2020, 5:44 p.m.