Description Usage Arguments Value Author(s)
Finds best local alignment for two PWMs.
| 1 2 3 4 | localPwmAlignment(pwm_left, pwm_right, divergence = shannonDivergence,
  unaligned_penalty = divergencePenaltyForUnaligned,
  try_reverse_complement = TRUE, base_distribution = NULL,
  length_normalization = FALSE)
 | 
| pwm_left | first PWM, a matrix of type matrix | 
| pwm_right | first PWM, a matrix of type matrix | 
| divergence | is a measure of difference between two pwm columns. Smaller is more similar. If you want to use non-uniform background distribution, provide your own function. | 
| unaligned_penalty | distance for unaligned columns at edges of matrixes. See divergencePenaltyForUnaligned as an example for providing your own function | 
| try_reverse_complement | If false the alignment will not be performed on reverse complements. If true, the input pwms should have column order of ACTG/ACGU. | 
| base_distribution | is a vector of length nrow(pwm) that is added to unaligned columns of pwms for comparing. If NULL, uniform distribution is used | 
| length_normalization | If true, will minimize the average divergence between PWMs. Otherwise will minimize the sum of divergences between positions. In both cases unalignes positions are compared to base_distribution and are counted when computing the alignment length. | 
list of length two containing the alignment and the divergence
Lando Andrey
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