auc_multifunc: Calculating AUC for functional groups from ranked lists

In EGAD: Extending guilt by association by degree

Description

The function calculates the AUC for a functional group analytically using an optimal ranked list of genes that indicates association between genes and groups.

Usage

auc_multifunc(annotations, optimallist)

Arguments

annotations	binary matrix indicating which list elements are in which functional groups.
optimallist	Ranked list (multifunctionality analysis, see calculate_multifunc).

Value

aucs array of aucs for each group in annotations

Examples

annotations <- c(rep(0,10))
annotations[c(1,3,5)] <- 1 
optimallist <- 10:1
aurocs_mf <- auc_multifunc(annotations, optimallist)

EGAD documentation built on Nov. 8, 2020, 8:31 p.m.