calculate_multifunc: Performing multifunctionality analysis

In EGAD: Extending guilt by association by degree

Description

The function performs multifunctionality analysis ([1]) for a set of annotated genes and creates a rank based optimallist. For annotations use an ontology that is large enough to serve as a prior (e.g. GO, Phenocarta).

Usage

calculate_multifunc(genes.labels)

Arguments

genes.labels

Annotation matrix

Value

gene.mfs Returns matrix with evaluation of gene function prediction by given labels:

Examples

genes.labels <- matrix( sample(c(0,1), 100, replace=TRUE),ncol=10,nrow=10)
rownames(genes.labels) = paste('gene', 1:10, sep='')
colnames(genes.labels) = paste('label', 1:10, sep='')
mf <- calculate_multifunc(genes.labels)

EGAD documentation built on Nov. 8, 2020, 8:31 p.m.