EventPointer is an R package to identify alternative splicing events that involve either simple (case-control experiment) or complex experimental designs such as time course experiments and studies including paired-samples. The algorithm can be used to analyze data from either junction arrays (Affymetrix Arrays) or sequencing data (RNA-Seq). The software returns a data.frame with the detected alternative splicing events: gene name, type of event (cassette, alternative 3',...,etc), genomic position, statistical significance and increment of the percent spliced in (Delta PSI) for all the events. The algorithm can generate a series of files to visualize the detected alternative splicing events in IGV. This eases the interpretation of results and the design of primers for standard PCR validation.
Package details |
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Author | Juan Pablo Romero, Juan A. Ferrer-Bonsoms, Pablo Sacristan, Ander Muniategui, Fernando Carazo, Ander Aramburu, Angel Rubio |
Bioconductor views | AlternativeSplicing DifferentialSplicing ImmunoOncology RNASeq Sequencing TimeCourse Transcription mRNAMicroarray |
Maintainer | Juan Pablo Romero <jpromero@ceit.es> |
License | Artistic-2.0 |
Version | 2.8.0 |
URL | https://github.com/jpromeror/EventPointer |
Package repository | View on Bioconductor |
Installation |
Install the latest version of this package by entering the following in R:
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