whippetTranscriptChangeSummary: Compare open reading frames for whippet differentially...

Description Usage Arguments Value Author(s) See Also Examples

View source: R/quickAnalysis.R

Description

Compare open reading frames for whippet differentially spliced events

Usage

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whippetTranscriptChangeSummary(whippetDataSet, gtf.all = NULL, BSgenome,
  eventTypes = "all", exons = NULL, transcripts = NULL, NMD = FALSE,
  exportGTF = NULL)

Arguments

whippetDataSet

whippetDataSet generated from readWhippetDataSet()

gtf.all

GRanges gtf annotation (can be used instead of specifying exons and transcripts)

BSgenome

BSGenome object containing the genome for the species analysed

eventTypes

which event type to filter for? default = "all"

exons

GRanges gtf annotation of exons

transcripts

GRanges gtf annotation of transcripts

NMD

Use NMD predictions? (Note: notNMD must be installed to use this feature)

exportGTF

file name to export alternative isoform GTFs (default=NULL)

Value

data.frame containing signficant whippet diff data and ORF change summaries

Author(s)

Beth Signal

See Also

Other whippet data processing: coordinates, diffSplicingResults, filterWhippetEvents, formatWhippetEvents, junctions, readCounts, readWhippetDIFFfiles, readWhippetDataSet, readWhippetJNCfiles, readWhippetPSIfiles

Examples

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whippetFiles <- system.file("extdata","whippet/",
package = "GeneStructureTools")
wds <- readWhippetDataSet(whippetFiles)
wds <- filterWhippetEvents(wds)

gtf <- rtracklayer::import(system.file("extdata","example_gtf.gtf",
package = "GeneStructureTools"))
g <- BSgenome.Mmusculus.UCSC.mm10::BSgenome.Mmusculus.UCSC.mm10
whippetTranscriptChangeSummary(wds, gtf.all=gtf,BSgenome = g)

GeneStructureTools documentation built on Nov. 8, 2020, 6:04 p.m.