sigInteractorsDIGGIT: Filter interactions from NES (DIGGIT) scores and...

Description Usage Arguments Value

View source: R/make.interactions.r

Description

Use this version in the Bayes model to rank TFs

Usage

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sigInteractorsDIGGIT(
  corrected.scores,
  nes.scores,
  cindy,
  p.thresh = 0.05,
  cindy.only = TRUE
)

Arguments

corrected.scores

A list indexed by the genomic event/gene with corresponding pvals and qvals for each TF

nes.scores

Matrix with tfs as columns, rows are genomic events

cindy

CINDy algorithm output matrix

p.thresh

P-value threshold (default=0.05)

cindy.only

Consider only CINDy validated interactions (default=TRUE)

Value

a list (indexed by VIPER protein) of significant genomic interactions and associated pvals over the background (null TF) model, and NES scores


MOMA documentation built on Nov. 8, 2020, 6:01 p.m.