edgeProp: A function to estimate the edge proportion of a y2h induced...

In ScISI: In Silico Interactome

Description

This function first creates the Y2H symmetric adjacency matrix on a protein complex (as we ignore directionality). Then it calculates an estimate for the proportion of edges the complex might have with high probability (if the sampling is unbaised and without error). In addition to this statistic, it also generates an instance of graph, specifically a graphNEL, on the adjcency matrix.

Usage

edgeProp(comp, compB2P, sampled)

Arguments

comp	A character vector of the constitutent members of the protein complex of interest
compB2P	A named list; the names correspond to constituent proteins used as baits and the entries are the found hits (prey)
sampled	A character vector of constituent members used as baits

Value

eProp	The estimated edge proportion of the complex
y2hGraph	A graphNEL instance of graph

Author(s)

T Chiang

ScISI documentation built on Nov. 8, 2020, 5:48 p.m.