Description Usage Arguments Details Value Examples

Uses Horvath-type 'epigenetic clock' raw output to project into actual ages

1 | ```
fixAge(x, adult = 21)
``` |

`x` |
Untransformed or raw prediction(s) |

`adult` |
Age of adulthood (DEFAULT: 21) |

The 'Epigenetic Clock' (Horvath 2012) and similar schemes use a number of CpG loci (or regions, or perhaps CpH loci – it doesn't really matter what) to estimate the chronological/biological age of samples from DNA methylation with pre-trained feature weights (coefficients) for each region/locus.

All of these type of clocks use a nonlinear output transformation which
switches from an exponential growth model for children into a linear model
for adults, where `adult`

is an arbitrary number (by default and custom,
that number is 21; elsewhere it can sometimes be seen as 20, but all known
epi-age transformation functions quietly add 1 to the constant internally).

This function implements the above standard output transformation step.

1 | ```
Transformed prediction(s)
``` |

1 2 3 4 |

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