BCellMA: B Cell Receptor Somatic Hyper Mutation Analysis

Includes a set of functions to analyze for instance nucleotide frequencies as well as transition and transversion. Can reconstruct germline sequences based on the international ImMunoGeneTics information system (IMGT/HighV-QUEST) outputs, calculate and plot the difference (%) of nucleotides at 6 positions around a mutation to identify and characterize hotspot motifs as well as calculate and plot average mutation frequencies of nucleotide mutations resulting in amino acid substitution.

Package details

AuthorOlena Ohlei <olena.ohlei@student.uni-luebeck.de>
MaintainerOlena Ohlei <olena.ohlei@student.uni-luebeck.de>
LicenseGPL (>= 2)
URL https://www.r-project.org
Package repositoryView on CRAN
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BCellMA documentation built on May 1, 2019, 7:58 p.m.