The calculation was obtained according bcRep package in R language. Every combination of two families was summarized and divided by the sum of all combinations across each group.
"V_GENE_and_allele" colums from IMGT/HighV-Quest table 1 coled "1_Summary.txt"
"J_GENE_and_allele" or "D_GENE_and_allele" colums from IMGT/HighV-Quest table 1 coled "1_Summary.txt"
Output is the data matrix of gene/gene ratios of two gene families.
Bischof J. and Ibrahim SM. bcRep: R Package for Comprehensive Analysis of B Cell Receptor Repertoire Data. PLoS One. 11(8):e0161569, 2016. doi: 10.1371/journal.pone.0161569.
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