A comprehensive synergy/antagonism analyses of drug combinations with quality graphics and data. The analyses can be performed by Bliss independence and Loewe additivity models. 'COMBIA' provides improved statistical analysis and makes only very weak assumption of data variability while calculating bootstrap intervals (BIs). It is based on heteroscedasticity controlled resampling (bootstrapping) and includes a global (omnibus) test. Finally, package shows analyzed data, 2D and 3D plots ready to use in research publications. 'COMBIA' does not require manual data entry. Data can be directly input from wet lab experimental platforms for example fluostar, automated robots etc. One only needs to call a single function, analyzeCOMBO(), to perform all analysis (examples are provided with sample data).
|Maintainer||Muhammad Kashif <[email protected]>|
|License||GPL (>= 2)|
|Package repository||View on CRAN|
Install the latest version of this package by entering the following in R:
Any scripts or data that you put into this service are public.
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.