loeweModel: This function applies Loewe Model

In COMBIA: Synergy/Antagonism Analyses of Drug Combinations

Description

This function applies Loewe Model

Usage

loeweModel(xConcentration, yConcentration, drugYObs_Mean, drugXObs_Mean)

Arguments

xConcentration	X drug concentrations
yConcentration	Y drug concentrations
drugYObs_Mean	Mean of y drug observations
drugXObs_Mean	Mean of x drug observations

Value

Loewe Model values

Author(s)

Muhammad kashif

Examples

xConcentration <- c(0.00,0.20, 0.39,  0.78,  1.56, 3.12, 6.25, 12.50, 25.00, 50.0) 
yConcentration <- c(128,  64,  32,  16,   8,   4,   2,   0)
drugXObs_Mean <- c(0.9747255, 0.9197924, 0.9520692, 0.9517162, 0.9032701, 0.7892114,
                     0.6768190, 0.6524227, 0.4561164)
drugYObs_Mean <- rev( c( 0.93, 0.89, 0.73, 0.42, 0.24, 0.21, 0.11) )
rslt <- loeweModel( xConcentration, yConcentration, drugYObs_Mean, drugXObs_Mean)

Example output

Loading required package: hash
hash-3.0.1 provided by Decision Patterns

Loading required package: gdata
sh: 1: cannot create /dev/null: Permission denied
gdata: Unable to locate valid perl interpreter
gdata: 
gdata: read.xls() will be unable to read Excel XLS and XLSX files
gdata: unless the 'perl=' argument is used to specify the location of a
gdata: valid perl intrpreter.
gdata: 
gdata: (To avoid display of this message in the future, please ensure
gdata: perl is installed and available on the executable search path.)
sh: 1: cannot create /dev/null: Permission denied
gdata: Unable to load perl libaries needed by read.xls()
gdata: to support 'XLX' (Excel 97-2004) files.

gdata: Unable to load perl libaries needed by read.xls()
gdata: to support 'XLSX' (Excel 2007+) files.

gdata: Run the function 'installXLSXsupport()'
gdata: to automatically download and install the perl
gdata: libaries needed to support Excel XLS and XLSX formats.

Attaching package: 'gdata'

The following object is masked from 'package:stats':

    nobs

The following object is masked from 'package:utils':

    object.size

The following object is masked from 'package:base':

    startsWith

Loading required package: lattice
Loading required package: latticeExtra
Loading required package: RColorBrewer
Loading required package: oro.nifti
oro.nifti 0.7.2

COMBIA documentation built on May 2, 2019, 7:23 a.m.