DIscBIO: A User-Friendly Pipeline for Biomarker Discovery in Single-Cell Transcriptomics

An open, multi-algorithmic pipeline for easy, fast and efficient analysis of cellular sub-populations and the molecular signatures that characterize them. The pipeline consists of four successive steps: data pre-processing, cellular clustering with pseudo-temporal ordering, defining differential expressed genes and biomarker identification. More details on Ghannoum et. al. (2021) <doi:10.3390/ijms22031399>. This package implements extensions of the work published by Ghannoum et. al. (2019) <doi:10.1101/700989>.

Getting started

Package details

AuthorSalim Ghannoum [aut, cph], Alvaro Köhn-Luque [aut, ths], Waldir Leoncio [cre, aut], Damiano Fantini [ctb]
MaintainerWaldir Leoncio <w.l.netto@medisin.uio.no>
LicenseMIT + file LICENSE
Version1.2.2
URL https://github.com/ocbe-uio/DIscBIO
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("DIscBIO")

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DIscBIO documentation built on Nov. 6, 2023, 5:08 p.m.