MotifEnrichment: 'MotifEnrichment'

In MOCHA: Modeling for Single-Cell Open Chromatin Analysis

MotifEnrichment

Description

Test for enrichment of motifs within Group1 against a background Group2 using a hypergeometric t-test.

Usage

MotifEnrichment(Group1, Group2, motifPosList, type = NULL)

Arguments

Group1	A GRanges object, such as a set of significant differential tiles.
Group2	A GRanges object containing background regions, non-overlapping with Group1
motifPosList	A GRangesList of motifs and positions for each motif. Must be named for each motif.
type	Optional, name of a metadata column in Group1 and Group2 to test for enrichment the number of unique entries in column given by 'type'. Default is NULL, which tests the number of Ranges.

Value

A data.frame containing enrichment for each group

MOCHA documentation built on May 29, 2024, 2:25 a.m.