MRConMix-class | R Documentation |
An object containing the estimate produced using the contamination mixture method as well as various statistics.
Exposure
The names of the exposure variables.
Outcome
The name of the outcome variable.
Psi
The value of the standard deviation of the distribution of invalid estimands (default is 1.5 times the standard deviation of the ratio estimates).
Estimate
The causal estimate from the contamination mixture method.
CIRange
The confidence interval for Estimate
based on a grid search.
CILower
The lower limit of the confidence interval. If the confidence interval contains multiple ranges, then lower limits of all ranges will be reported.
CIUpper
The upper limit of the confidence interval. If the confidence interval contains multiple ranges, then upper limits of all ranges will be reported.
CIMin
The smallest value used in the search to find the confidence interval.
CIMax
The largest value used in the search to find the confidence interval.
CIStep
The step size used in the search to find the confidence interval.
Pvalue
The p-value associated with the estimate calculated using the likelihood function and a chi-squared distribution.
Valid
The numbers of genetic variants that were considered valid instruments at the causal estimate.
ValidSNPs
The names of genetic variants that were considered valid instruments at the causal estimate.
Alpha
The significance level used in constructing the confidence interval (default is 0.05).
SNPs
The number of SNPs that were used in the calculation.
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