MRConMix-class: MRConMix Class
In MendelianRandomization: Mendelian Randomization Package

MRConMix-class

R Documentation

MRConMix Class

An object containing the estimate produced using the contamination mixture method as well as various statistics.

Exposure: The names of the exposure variables.
Outcome: The name of the outcome variable.
Psi: The value of the standard deviation of the distribution of invalid estimands (default is 1.5 times the standard deviation of the ratio estimates).
Estimate: The causal estimate from the contamination mixture method.
CIRange: The confidence interval for Estimate based on a grid search.
CILower: The lower limit of the confidence interval. If the confidence interval contains multiple ranges, then lower limits of all ranges will be reported.
CIUpper: The upper limit of the confidence interval. If the confidence interval contains multiple ranges, then upper limits of all ranges will be reported.
CIMin: The smallest value used in the search to find the confidence interval.
CIMax: The largest value used in the search to find the confidence interval.
CIStep: The step size used in the search to find the confidence interval.
Pvalue: The p-value associated with the estimate calculated using the likelihood function and a chi-squared distribution.
Valid: The numbers of genetic variants that were considered valid instruments at the causal estimate.
ValidSNPs: The names of genetic variants that were considered valid instruments at the causal estimate.
Alpha: The significance level used in constructing the confidence interval (default is 0.05).
SNPs: The number of SNPs that were used in the calculation.