Calculates log-likelihood with uncorrelated variants in two-sample setting (no correlation from sample overlap)

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Description

Internal function for calculating log-likelihood for for maximum-likelihood method.

Usage

1
loglikelihood(param, x, sigmax, y, sigmay)

Arguments

param

Parameters in the model.

x

Genetic associations with the exposure.

sigmax

Standard errors of associations with the exposure.

y

Genetic associations with the outcome.

sigmay

Standard errors of genetic associations with the outcome.

Details

None.

Value

Log-likelihood.

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