het.weight: Heterogeneity-penalized weight function
In MendelianRandomization: Mendelian Randomization Package
View source: R/mr_hetpen-methods.R
het.weight R Documentation
Heterogeneity-penalized weight function
Description
Internal function for calculating heterogeneity-penalized weights.
Usage
het.weight(prob.valid.inst, bx, by, byse)
Arguments
prob.valid.inst
Probability (prior) of a genetic variant being a valid instrument.
bx
Genetic associations with risk factor.
by
Genetic associations with outcome.
byse
Standard errors of genetic associations with outcome.
Details
None.
Value
Heterogeneity-penalized weight.
Examples
het.weight(0.5, calcium, fastgluc, fastglucse)
MendelianRandomization documentation built on Aug. 9, 2023, 1:05 a.m.
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View source: R/mr_hetpen-methods.R
| het.weight | R Documentation |
Heterogeneity-penalized weight function
Description
Internal function for calculating heterogeneity-penalized weights.
Usage
het.weight(prob.valid.inst, bx, by, byse)
Arguments
prob.valid.inst |
Probability (prior) of a genetic variant being a valid instrument. |
bx |
Genetic associations with risk factor. |
by |
Genetic associations with outcome. |
byse |
Standard errors of genetic associations with outcome. |
Details
None.
Value
Heterogeneity-penalized weight.
Examples
het.weight(0.5, calcium, fastgluc, fastglucse)
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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