Man pages for MultiSEp
Predict Synthetic Lethality and Other Gene Dependency Relationships from Multiomics Data
| depMapCRISPRscores_subset | Example CRISPR score input matrix |
| depMapMUT_small | Example mutation data input matrix |
| depMapMUT_subset | Example mutation data input matrix |
| depMapTissue_subset | Example tissue data input matrix |
| depMapXPR_small | Example gene expression input matrix |
| depMapXPR_subset | Example gene expression input matrix |
| Formatted_MUTimpactMatrix | The output of 'mts_formatMatrix()' function for an example... |
| mixModelClusters_depMapCRISPR | Clusters of samples (cell lines) from the... |
| mixModelClusters_depMapXPR | Clusters output from the 'mts_mixModelCluster' function for a... |
| mixModelClusters_vignette | Clusters output from the 'mts_mixModelCluster' function for a... |
| mRes | Example results for the 'mts_Mutation' function. |
| mts_ClusterAvg | Determine average CRISPR score values for gene expression... |
| mts_Crispr | Investigate Gene Dependency Relationships with CRISPR and... |
| mts_crisprPartition | Partition CRISPR gene effect scores |
| mts_CrisprTS | Predict tissue-specific gene dependency relationships,... |
| mts_formatMatrix | Format a matrix into a list of data frames that capture gene... |
| mts_GeneDepCrispr | CRISPR and gene expression gene-dependency prediction... |
| mts_GeneDepID | CRISPR vs gene expression induced dependency pipeline... |
| mts_GeneDepMutation | Mutation vs gene expression gene-dependency prediction |
| mts_genepairsChunkGeneration | Generate '.RData' files containing subsets of gene pairs |
| mts_InducedDependency | Predict 'induced dependency' relationships, evaluating... |
| mts_mixModelCluster | Cluster continuous data with Gaussian Mixture Modelling |
| mts_mixModelCluster_XPR | Cluster gene expression data with Gaussian Mixture Modelling |
| mts_Mutation | Integrate gene cluster assignments with mutation data |
| mts_omics | Predict synthetic lethality and other dependency... |
| mts_pairwiseExpressionPlot | Visualise pairwise gene expression data with MultiSEp cluster... |
| mts_patternDetection | Predict Gene Dependency Relationship Patterns, including... |
| mts_plotClusterDistribution | Visualise samples and pairwise gene expression clusters |
| mts_plotCRISPRGeneCluster | Visualise CRISPR and expression data (SynLeGG methods). |
| mts_plotMutation | Visualise clusters for one gene with the mutation status of... |
| mts_targetCoverageFromMutations | Predict the therapeutic population coverage achieved by... |
| mts_tests | Unit Tests for the MultiSEp package |
| multisepCrisprList | Example Multisep t-test CRISPR vs XPR results object. |
| multisepList | Example results from mts_clusterAvg() |
| MUT_impactMatrix | Example mutation impact matrix |
