# NMFstd-class: NMF Model - Standard model In NMF: Algorithms and Framework for Nonnegative Matrix Factorization (NMF)

 NMFstd-class R Documentation

## NMF Model - Standard model

### Description

This class implements the standard model of Nonnegative Matrix Factorization. It provides a general structure and generic functions to manage factorizations that follow the standard NMF model, as defined by Lee et al. (2001).

### Details

Let V be a n \times m non-negative matrix and r a positive integer. In its standard form (see references below), a NMF of V is commonly defined as a pair of matrices (W, H) such that:

V \equiv W H,

where:

• W and H are n \times r and r \times m matrices respectively with non-negative entries;

• \equiv is to be understood with respect to some loss function. Common choices of loss functions are based on Frobenius norm or Kullback-Leibler divergence.

Integer r is called the factorization rank. Depending on the context of application of NMF, the columns of W and H are given different names:

columns of W

basis vector, metagenes, factors, source, image basis

columns of H

mixture coefficients, metagene sample expression profiles, weights

rows of H

basis profiles, metagene expression profiles

NMF approaches have been successfully applied to several fields. The package NMF was implemented trying to use names as generic as possible for objects and methods.

The following terminology is used:

samples

the columns of the target matrix V

features

the rows of the target matrix V

basis matrix

the first matrix factor W

basis vectors

the columns of first matrix factor W

mixture matrix

the second matrix factor H

mixtures coefficients

the columns of second matrix factor H

However, because the package NMF was primarily implemented to work with gene expression microarray data, it also provides a layer to easily and intuitively work with objects from the Bioconductor base framework. See bioc-NMF for more details.

### Slots

W

A matrix that contains the basis matrix, i.e. the first matrix factor of the factorisation

H

A matrix that contains the coefficient matrix, i.e. the second matrix factor of the factorisation

bterms

a data.frame that contains the primary data that define fixed basis terms. See bterms.

ibterms

integer vector that contains the indexes of the basis components that are fixed, i.e. for which only the coefficient are estimated.

IMPORTANT: This slot is set on construction of an NMF model via nmfModel and is not recommended to not be subsequently changed by the end-user.

cterms

a data.frame that contains the primary data that define fixed coefficient terms. See cterms.

icterms

integer vector that contains the indexes of the basis components that have fixed coefficients, i.e. for which only the basis vectors are estimated.

IMPORTANT: This slot is set on construction of an NMF model via nmfModel and is not recommended to not be subsequently changed by the end-user.

### Methods

.basis

signature(object = "NMFstd"): Get the basis matrix in standard NMF models

This function returns slot W of object.

.basis<-

signature(object = "NMFstd", value = "matrix"): Set the basis matrix in standard NMF models

This function sets slot W of object.

bterms<-

signature(object = "NMFstd"): Default method tries to coerce value into a data.frame with as.data.frame.

.coef

signature(object = "NMFstd"): Get the mixture coefficient matrix in standard NMF models

This function returns slot H of object.

.coef<-

signature(object = "NMFstd", value = "matrix"): Set the mixture coefficient matrix in standard NMF models

This function sets slot H of object.

cterms<-

signature(object = "NMFstd"): Default method tries to coerce value into a data.frame with as.data.frame.

fitted

signature(object = "NMFstd"): Compute the target matrix estimate in standard NMF models.

The estimate matrix is computed as the product of the two matrix slots W and H:

V ~ W H

ibterms

signature(object = "NMFstd"): Method for standard NMF models, which returns the integer vector that is stored in slot ibterms when a formula-based NMF model is instantiated.

icterms

signature(object = "NMFstd"): Method for standard NMF models, which returns the integer vector that is stored in slot icterms when a formula-based NMF model is instantiated.

### References

Lee DD and Seung H (2001). "Algorithms for non-negative matrix factorization." _Advances in neural information processing systems_. <URL: http://scholar.google.com/scholar?q=intitle:Algorithms+for+non-negative+matrix+factorization>.

Other NMF-model: initialize,NMFOffset-method, NMFns-class, NMFOffset-class

### Examples



# create a completely empty NMFstd object
new('NMFstd')

# create a NMF object based on one random matrix: the missing matrix is deduced
# Note this only works when using factory method NMF
n <- 50; r <- 3;
w <- rmatrix(n, r)
nmfModel(W=w)

# create a NMF object based on random (compatible) matrices
p <- 20
h <- rmatrix(r, p)
nmfModel(W=w, H=h)

# create a NMF object based on incompatible matrices: generate an error
h <- rmatrix(r+1, p)
try( new('NMFstd', W=w, H=h) )
try( nmfModel(w, h) )

# Giving target dimensions to the factory method allow for coping with dimension
# incompatibilty (a warning is thrown in such case)
nmfModel(r, W=w, H=h)


NMF documentation built on Nov. 18, 2022, 5:10 p.m.