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#' k_separated_bigrams_pssm feature vector
#' @description This feature is almost identical to the \code{\link{dpc_pssm}} feature, and in fact the DPC feature is part of
#'this feature (for k=1) and for two different columns, considers rows that differ by the size of the unit k.
#' @param pssm_name is name of PSSM Matrix file
#' @param k a parameter that specifies separated length between amino acids
#' @import utils
#' @return a feature vector of length 400
#' @references
#' Saini, H., et al.(2016) Protein Fold Recognition Using Genetic Algorithm Optimized Voting Scheme and Profile
#' Bigram.
#' @export
#' @examples
#' X<-k_separated_bigrams_pssm(system.file("extdata", "C7GQS7.txt.pssm", package="PSSMCOOL"),1)
k_separated_bigrams_pssm<-function(pssm_name,k=1){
x<-read.delim(pssm_name,skip = 2,sep = "",header = FALSE)
x<-x[-1,-c(1,23:44)]
d<-which(x=="Lambda")
if(length(d)!=0){
x<-x[-c(d:dim(x)[1]),]
}
x<-x[,-1]
colnames(x)<-NULL
rownames(x)<-NULL
x<-as.matrix(x)
mode(x)<-"integer"
m2<-x
m2<-1/(1+exp(-m2))
L<-dim(m2)[1]
j<-1
km<-matrix(0,20,20)
s<-0
for (m in 1:20) {
for (n in 1:20) {
for (i in 1:(L-k)) {
s <- s+m2[i,m]*m2[i+k,n]
}
km[m,n]<-s
s<-0
}
}
v<-c()
for(i in 1:20){
v<-c(v,km[i,])
}
v<-round(v,digits = 4)
return(v)
}
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