Description Usage Arguments Value
View source: R/PedSim_Functions.R
Create new seed founder for pedigree.
1 | create_founder(FamID, GRR, carrier_prob, RVfounder, founder_byears)
|
FamID |
Numeric. The family ID to assign to the simulated pedigree. |
GRR |
Numeric. The genetic relative-risk of disease, i.e. the relative-risk of disease for individuals who carry at least one copy of the causal variant. Note: When simulating diseases with multiple subtypes |
carrier_prob |
Numeric. The carrier probability for all causal variants with relative-risk of disease |
RVfounder |
Logical. Indicates if all pedigrees segregate the rare, causal variant. By default, |
founder_byears |
Numeric vector of length 2. The span of years from which to simulate, uniformly, the birth year for the founder who introduced the rare variant to the pedigree. |
new_founder_info
the pedigree information for the new mate.
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