Description Usage Arguments Details Value Author(s) References Examples

View source: R/refinedBoundaries.R

Generate lower and upper bounds for programs calculating the secondary endpoint's type I error when the correlation rho between the primary endpoint and the secondary endpoint equals 1.

1 | ```
cdBoundary(cvec, dvec, gammaVec, dlt, upper = TRUE)
``` |

`cvec` |
primary boundary. |

`dvec` |
secondary boundary. |

`gammaVec` |
square root of information vector. |

`dlt` |
test statistic of the primary endpoint follows a normal distribution with mean |

`upper` |
type of bounds, upper bound is |

This function generates upper and lower bounds for further computation. For more details, refer to Tamhane et al. (2017+), section 4.2.

lower and upper bounds for programs calculating the secondary endpoint's type I error when the correlation rho is 1.

Jiangtao Gou

Tamhane, A. C., Gou, J., Jennison, C., Mehta, C. R., and Curto, T. (2017+). A gatekeeping procedure to test a primary and a secondary endpoint in a group sequential design with multiple interim looks. *Biometrics*, to appear.

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gsrsb documentation built on May 29, 2017, 7:12 p.m.

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