ldPrimaryBoundary: Calculate Primary Boundaries, the Error Spending Approach

Description Usage Arguments Value Author(s) References See Also

View source: R/refinedBoundaries.R

Description

Primary boundaries calculation of Lan-DeMets OBF and POC.

Usage

1
ldPrimaryBoundary(tVec, alpha, type = 1, initIntvl = c(0.8, 8))

Arguments

tVec

a vector of information, gammaVec = sqrt(tVec).

alpha

significance level

type

type of sequential procedure. OBF is 1, POC is 2.

initIntvl

paramter for function uniroot (two numbers)

Value

a vector of primary boundaries.

Author(s)

Jiangtao Gou

References

Lan, K. K. G., and Demets, D. L. (1983). Discrete sequential boundaries for clinical trials. Biometrika 70, 659-663.

Tamhane, A. C., Gou, J., Jennison, C., Mehta, C. R., and Curto, T. (2017+). A gatekeeping procedure to test a primary and a secondary endpoint in a group sequential design with multiple interim looks. Biometrics, to appear.

See Also

primaryBoundary


gsrsb documentation built on May 29, 2017, 7:12 p.m.