secControl: Difference between the Error Rate and Significance Level,...

In gsrsb: Group Sequential Refined Secondary Boundary

Difference between the Error Rate and Significance Level, Standard Approach

Description

Calculate the difference between the error rate and significance level for the secondary endpoint, standard (original) approach.

Usage

secControl(d, alpha, cvec, gammaVec, ExtrmLoc, type = 2)

Arguments

d	boundary of secondary endpoint at the final look (a number, d_(K))
alpha	targeted significance level for the secondary endpoint
cvec	a vector of calculated primary boundaries
gammaVec	square root of information
ExtrmLoc	an integer between 1 and K, locate the maximum of type I error of secondary endpoint
type	type of sequential procedures. Type 1 OBF d, Type 2 POC d.

Value

difference between alpha and the calculated error rate.

Author(s)

Jiangtao Gou

References

Tamhane, A. C., Gou, J., Jennison, C., Mehta, C. R., and Curto, T. (2018). A gatekeeping procedure to test a primary and a secondary endpoint in a group sequential design with multiple interim looks. Biometrics, 74(1), 40-48.

See Also

ldSecControl

gsrsb documentation built on July 9, 2023, 6:02 p.m.